Assay Detail
Binding
CHEMBL4407168
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Inhibition of Plasmodium falciparum M1 aminopeptidase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Plasmodium falciparum |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Novel Human Aminopeptidase N Inhibitors: Discovery and Optimization of Subsite Binding Interactions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.84 | 6.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3765455 | — | — | 1 | 6.48 |
| CHEMBL29292 | UBENIMEX | 2.0 | 1 | 5.82 |
| CHEMBL2103847 | TOSEDOSTAT | 2.0 | 1 | 5.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3765455 | — | Ki | = | 331.0 | nM | 6.48 |
| CHEMBL29292 | UBENIMEX | Ki | = | 1530.0 | nM | 5.82 |
| CHEMBL2103847 | TOSEDOSTAT | Ki | = | 6150.0 | nM | 5.21 |