Assay Detail
Binding
CHEMBL4408770
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Competitive reversible inhibition of CDK7 (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Cyclin dependent kinase (CDK) inhibitors as anticancer drugs: Recent advances (2015-2019).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.23 | 7.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1801932 | — | — | 1 | 7.68 |
| CHEMBL4297488 | CT-7001 | 2.0 | 1 | 7.40 |
| CHEMBL1234833 | — | — | 1 | 6.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1801932 | — | IC50 | = | 21.0 | nM | 7.68 |
| CHEMBL4297488 | CT-7001 | IC50 | = | 40.0 | nM | 7.40 |
| CHEMBL1234833 | — | IC50 | = | 250.0 | nM | 6.60 |