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Assay Detail

CHEMBL4409301

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Binding
Binding affinity to kappa opioid receptor (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Kappa-type opioid receptor (CHEMBL237)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Progress in the development of more effective and safer analgesics for pain management.
Turnaturi R, Chiechio S, Salerno L, Rescifina A, Pittalà V, Cantarella G, Tomarchio E, Parenti C, Pasquinucci L.
Eur J Med Chem (2019) 183 : 111701 -111701
PubMed 31550662 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 2 8.96 9.23

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2381583 22-THIOCYANATOSALVINORIN A 1 9.23
CHEMBL4464797 1 8.68

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2381583 22-THIOCYANATOSALVINORIN A Kd = 0.59 nM 9.23
CHEMBL4464797 Kd = 2.1 nM 8.68