Assay Detail
Functional
CHEMBL4409785
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Antiviral activity against Influenza A virus A/WSN/33(H1N1) infected in MDCK cells assessed as inhibition of virus-induced cytopathic effect measured after 45 hrs by CellTiter-Glo luminescence assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Influenza A virus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design, synthesis and biological evaluation of amino acids-oleanolic acid conjugates as influenza virus inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.46 | 5.74 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1200340 | OSELTAMIVIR PHOSPHATE | 4.0 | 1 | 5.74 |
| CHEMBL4578422 | — | — | 1 | 5.18 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1200340 | OSELTAMIVIR PHOSPHATE | IC50 | = | 1820.0 | nM | 5.74 |
| CHEMBL4578422 | — | IC50 | = | 6640.0 | nM | 5.18 |