Assay Detail
Functional
CHEMBL4409822
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Japanese encephalitis virus infected in human TE671 cells assessed as reduction in virus entry at early stage by measuring decrease in NS3-positive cells treated immediately after viral infection followed by virus/compound mixture wash-out at 1 hr post-incubation followed by culturing of cells for 24 hrs by DAPI-staining based immunofluorescence analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Japanese encephalitis virus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Japanese encephalitis virus (CHEMBL613729) ↗| Type | ORGANISM |
| Organism | Japanese encephalitis virus |
Publication
Antiviral efficacy of bromo-anilino substituents of 4,5-dihydrofuran-3-carboxylate compound CW-33 against Japanese encephalitis virus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.70 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4578826 | — | — | 1 | 6.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4578826 | — | IC50 | = | 200.0 | nM | 6.70 |