Assay Detail
ADMET
CHEMBL4410326
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Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by resazurin reagent based assay
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | HepG2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
The plant-derived chalcone Xanthoangelol targets the membrane of Gram-positive bacteria.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.86 | 4.86 |
| IC90 | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL494083 | XANTHOANGELOL | — | 2 | 4.86 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL494083 | XANTHOANGELOL | IC50 | = | 13700.0 | nM | 4.86 |
| CHEMBL494083 | XANTHOANGELOL | IC90 | = | 37400.0 | nM | - |