Assay Detail
Binding
CHEMBL4413449
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human recombinant cPLA2 assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS analysis
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Substrate-Specific Inhibition Constants for Phospholipase A<sub>2</sub> Acting on Unique Phospholipid Substrates in Mixed Micelles and Membranes Using Lipidomics.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| XI50 | 1 | - | - |
| IC50 | 1 | 5.80 | 5.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4438490 | — | — | 2 | 5.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4438490 | — | IC50 | = | 1590.0 | nM | 5.80 |
| CHEMBL4438490 | — | XI50 | = | 0.0023 | uM | - |