Assay Detail
Functional
CHEMBL4414748
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antioxidant activity assessed as DPPH radical scavenging activity incubated for 30 mins under dark condition
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Discovery of a novel 2,5-dihydroxycinnamic acid-based 5-lipoxygenase inhibitor that induces apoptosis and may impair autophagic flux in RCC4 renal cancer cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.79 | 4.86 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL196 | ASCORBIC ACID | 4.0 | 1 | 4.86 |
| CHEMBL4579523 | — | — | 1 | 4.82 |
| CHEMBL131678 | — | — | 1 | 4.79 |
| CHEMBL4515200 | — | — | 1 | 4.76 |
| CHEMBL319244 | CAFFEIC ACID PHENETHYL ESTER | — | 1 | 4.74 |
| CHEMBL93 | ZILEUTON | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL196 | ASCORBIC ACID | IC50 | = | 13940.0 | nM | 4.86 |
| CHEMBL4579523 | — | IC50 | = | 15040.0 | nM | 4.82 |
| CHEMBL131678 | — | IC50 | = | 16410.0 | nM | 4.79 |
| CHEMBL4515200 | — | IC50 | = | 17330.0 | nM | 4.76 |
| CHEMBL319244 | CAFFEIC ACID PHENETHYL ESTER | IC50 | = | 18200.0 | nM | 4.74 |
| CHEMBL93 | ZILEUTON | IC50 | > | 100000.0 | nM | - |