Assay Detail
Functional
CHEMBL4415084
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Dengue virus 2 NGC infected in human HuH7 cells incubated for 48 hrs by viral titer reduction assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | dengue virus type 2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design, Synthesis, and Biological Evaluation of Substituted 4,6-Dihydrospiro[[1,2,3]triazolo[4,5-<i>b</i>]pyridine-7,3'-indoline]-2',5(3<i>H</i>)-dione Analogues as Potent NS4B Inhibitors for the Treatment of Dengue Virus Infection.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 7.00 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4446551 | — | — | 1 | 7.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4446551 | — | EC50 | = | 100.0 | nM | 7.00 |