Assay Detail
Binding
CHEMBL4415151
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Inhibition of CBR (unknown origin)
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Imidazopyridine-based selective and multifunctional ligands of biological targets associated with psychiatric and neurodegenerative diseases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.52 | 7.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL54349 | ALPIDEM | 4.0 | 1 | 7.58 |
| CHEMBL319567 | — | — | 1 | 6.42 |
| CHEMBL106237 | — | — | 1 | 5.56 |
| CHEMBL97269 | — | — | 1 | - |
| CHEMBL509917 | — | — | 1 | - |
| CHEMBL521186 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL54349 | ALPIDEM | IC50 | = | 26.0 | nM | 7.58 |
| CHEMBL319567 | — | IC50 | = | 380.0 | nM | 6.42 |
| CHEMBL106237 | — | IC50 | = | 2740.0 | nM | 5.56 |
| CHEMBL97269 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL509917 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL521186 | — | IC50 | > | 10000.0 | nM | - |