Assay Detail
Binding
CHEMBL4415206
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate preincubated for 30 mins followed by substrate addition and measured after 5 mins by Ellman's method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Electrophorus electricus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Labdanes, Withanolides, and Other Constituents from <i>Physalis nicandroides</i>.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.36 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL94 | PHYSOSTIGMINE | 3.0 | 1 | 8.52 |
| CHEMBL4577484 | — | — | 1 | 4.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL94 | PHYSOSTIGMINE | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL4577484 | — | IC50 | = | 64400.0 | nM | 4.19 |