Assay Detail
Functional
CHEMBL4415628
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Cytotoxicity against human SKBR3 cells assessed as inhibition of cell viability incubated for 72 hrs by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SK-BR-3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Yangpumicins F and G, Enediyne Congeners from Micromonospora yangpuensis DSM 45577.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.82 | 9.07 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4528553 | — | — | 1 | 9.07 |
| CHEMBL4472466 | — | — | 1 | 8.59 |
| CHEMBL4466320 | — | — | 1 | 7.62 |
| CHEMBL105 | MITOMYCIN | 4.0 | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4528553 | — | IC50 | = | 0.86 | nM | 9.07 |
| CHEMBL4472466 | — | IC50 | = | 2.56 | nM | 8.59 |
| CHEMBL4466320 | — | IC50 | = | 24.2 | nM | 7.62 |
| CHEMBL105 | MITOMYCIN | IC50 | = | 1000.0 | nM | 6.00 |