Assay Detail
Binding
CHEMBL4415659
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Inhibition of F1F0-ATP synthase in Escherichia coli
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Recent advancements in mechanistic studies and structure activity relationship of FoF1 ATP synthase inhibitor as antimicrobial agent.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.24 | 5.65 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4443647 | — | — | 1 | 5.65 |
| CHEMBL2064676 | — | — | 1 | 5.30 |
| CHEMBL4527165 | — | — | 1 | 5.30 |
| CHEMBL2064674 | — | — | 1 | 5.28 |
| CHEMBL4452203 | — | — | 1 | 5.22 |
| CHEMBL2064669 | — | — | 1 | 5.16 |
| CHEMBL412927 | MELITTIN | — | 1 | 5.11 |
| CHEMBL2064670 | — | — | 1 | 5.05 |
| CHEMBL2064675 | — | — | 1 | 5.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4443647 | — | IC50 | = | 2250.0 | nM | 5.65 |
| CHEMBL2064676 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL4527165 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL2064674 | — | IC50 | = | 5250.0 | nM | 5.28 |
| CHEMBL4452203 | — | IC50 | = | 6000.0 | nM | 5.22 |
| CHEMBL2064669 | — | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL412927 | MELITTIN | IC50 | = | 7840.0 | nM | 5.11 |
| CHEMBL2064670 | — | IC50 | = | 9000.0 | nM | 5.05 |
| CHEMBL2064675 | — | IC50 | = | 9000.0 | nM | 5.05 |