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Assay Detail

CHEMBL4415752

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Functional
Antitumor activity against human 518A2 cells by SRB assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type 518A2
Confidence 1 — Organism
Curated By Autocuration

Target

518A2 (CHEMBL4483222)
Type CELL-LINE
Organism Homo sapiens

Publication

Design and synthesis of pentacyclic triterpene conjugates and their use in medicinal research.
Hodon J, Borkova L, Pokorny J, Kazakova A, Urban M.
Eur J Med Chem (2019) 182 : 111653 -111653
PubMed 31499360 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.17 6.48

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL269277 BETULINIC ACID 1.0 1 6.48
CHEMBL4438846 1 5.85

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL269277 BETULINIC ACID IC50 = 330.0 nM 6.48
CHEMBL4438846 IC50 = 1400.0 nM 5.85