Assay Detail
Binding
CHEMBL4415960
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at human P2X4R transfected in 1321N1 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Development of High-Throughput Fluorescent-Based Screens to Accelerate Discovery of P2X Inhibitors from Animal Venoms.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.64 | 5.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1532400 | — | — | 1 | 5.80 |
| CHEMBL2180160 | — | — | 1 | 5.48 |
| CHEMBL2180179 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1532400 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL2180160 | — | IC50 | = | 3300.0 | nM | 5.48 |
| CHEMBL2180179 | — | IC50 | - | — | - |