Assay Detail
Binding
CHEMBL4416202
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to CDPK1 in Plasmodium falciparum 3D7 blood stage extract incubated for 1 hr by kinobeads based pull down assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Plasmodium falciparum 3D7 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Calcium-dependent protein kinase 1 (CHEMBL1908387) ↗| Type | SINGLE PROTEIN |
| Organism | Plasmodium falciparum |
Publication
Development of Chemical Entities Endowed with Potent Fast-Killing Properties against <i>Plasmodium falciparum</i> Malaria Parasites.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 6.49 | 7.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4591417 | — | — | 1 | 7.30 |
| CHEMBL4461850 | — | — | 1 | 5.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4591417 | — | Kd | = | 50.0 | nM | 7.30 |
| CHEMBL4461850 | — | Kd | = | 2100.0 | nM | 5.68 |