Assay Detail
ADMET
CHEMBL4416677
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Cytotoxicity against human MRC5 cells assessed as reduction in cell growth after 72 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | MRC5 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Macroline-Sarpagine Bisindole Alkaloids with Antiproliferative Activity from Alstonia penangiana.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.10 | 5.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4449333 | — | — | 1 | 5.10 |
| CHEMBL4460874 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4449333 | — | IC50 | = | 7900.0 | nM | 5.10 |
| CHEMBL4460874 | — | IC50 | > | 10000.0 | nM | - |