Assay Detail
Binding
CHEMBL4417802
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of RGS17 (unknown origin) in presence of and ATP Galpha-o by Malachite green steady-state GTPase assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Regulator of G-protein signaling 17 (CHEMBL4295974) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Therapeutic compounds and methods
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.88 | 5.20 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL301982 | CELASTROL | — | 1 | 5.20 |
| CHEMBL555017 | GAMBOGIC ACID | — | 1 | 4.97 |
| CHEMBL490129 | SANGUINARIUM CHLORIDE | 2.0 | 1 | 4.90 |
| CHEMBL1438439 | IRIGENOL | — | 1 | 4.45 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL301982 | CELASTROL | IC50 | = | 6359.0 | nM | 5.20 |
| CHEMBL555017 | GAMBOGIC ACID | IC50 | = | 10790.0 | nM | 4.97 |
| CHEMBL490129 | SANGUINARIUM CHLORIDE | IC50 | = | 12520.0 | nM | 4.90 |
| CHEMBL1438439 | IRIGENOL | IC50 | = | 35510.0 | nM | 4.45 |