Assay Detail

CHEMBL4418636

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Functional

Growth inhibition of human A498 cells

ChEMBL ↗

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Target

A498 (CHEMBL614516) ↗

Open DB target context

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Primary target A498

CHEMBL614516

Anchored from Assay target.

Protein identity A498

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	A498
Confidence	1 — Organism
Curated By	Autocuration

Target

A498 (CHEMBL614516) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Klf5 modulators

(2015)

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.38	6.38

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL4462423	—	—	1	6.38

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL4462423	—	IC50	=	420.0	nM	6.38