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Assay Detail

CHEMBL4419277

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Growth inhibition of human NCI-H2122 cells incubated for 3 days
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type NCI-H2122
Confidence 1 — Organism
Curated By Autocuration

Target

NCI-H2122 (CHEMBL1075533)
Type CELL-LINE
Organism Homo sapiens

Publication

Methods and compositions for inhibiting cnksr1
(2018)

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 6 4.54 4.58

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4542845 1 4.58
CHEMBL1422005 1 4.57
CHEMBL2030270 1 4.47
CHEMBL4446354 1 -
CHEMBL4528582 1 -
CHEMBL4576938 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4542845 IC50 = 26000.0 nM 4.58
CHEMBL1422005 IC50 = 27000.0 nM 4.57
CHEMBL2030270 IC50 = 34000.0 nM 4.47
CHEMBL4446354 IC50 > 100000.0 nM -
CHEMBL4528582 IC50 > 100000.0 nM -
CHEMBL4576938 IC50 > 100000.0 nM -