Assay Detail
Functional
CHEMBL4419418
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity in human HT-29 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
3
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HT-29 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Substituted n-([1,1''-biphenyl]-3-yl)-[1,1''-biphenyl]-3-carboxamide analogs as inhibitors for beta-catenin/b-cell lymphoma 9 interactions
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.12 | 5.53 |
| Inhibition | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4074243 | — | — | 2 | 5.53 |
| CHEMBL484853 | CARNOSIC ACID | — | 1 | 4.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4074243 | — | IC50 | = | 2970.0 | nM | 5.53 |
| CHEMBL484853 | CARNOSIC ACID | IC50 | = | 20190.0 | nM | 4.70 |
| CHEMBL4074243 | — | Inhibition | - | % | - |