Assay Detail
Binding
CHEMBL4419736
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to recombinant human LARG (765 to 1138 residues) K979A mutant by microscale thermophoresis analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Rho guanine nucleotide exchange factor 12 (CHEMBL4523477) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Small-molecule inhibitors targeting g-protein-coupled rho guanine nucleotide exchange factors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 5.67 | 5.67 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL485210 | — | — | 1 | 5.67 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL485210 | — | Kd | = | 2121.0 | nM | 5.67 |