Assay Detail
Binding
CHEMBL4419739
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to recombinant human LARG (765 to 1138 residues) containing DH-PH catalytic module by microscale thermophoresis analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Rho guanine nucleotide exchange factor 12 (CHEMBL4523477) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Small-molecule inhibitors targeting g-protein-coupled rho guanine nucleotide exchange factors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 7.19 | 7.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL485210 | — | — | 1 | 7.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL485210 | — | Kd | = | 65.0 | nM | 7.19 |