Assay Detail
Binding
CHEMBL4420246
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Uncompetitive inhibition of recombinant chicken RPE65 assessed as reduction in substrate Vmax and Km using DOPC:DLPC liposomes with all-trans-retinyl palmitate as substrate by Lineweaver-Burk analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Gallus gallus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Compositions and methods of inhibiting retinal degeneration
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 4.28 | 4.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL13210 | — | — | 1 | 4.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL13210 | — | Ki | = | 53000.0 | nM | 4.28 |