Assay Detail
Binding
CHEMBL4421179
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of GFP-tagged mouse LOX expressed in in MDCK cysts by confocal imaging analysis
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Cell Type | MDCK |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Methylamine derivatives as lysysl oxidase inhibitors for the treatment of cancer
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.16 | 6.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4522646 | — | — | 1 | 6.72 |
| CHEMBL4548488 | — | — | 1 | 6.16 |
| CHEMBL4441173 | — | — | 1 | 5.60 |
| CHEMBL4434955 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4522646 | — | IC50 | = | 190.0 | nM | 6.72 |
| CHEMBL4548488 | — | IC50 | = | 700.0 | nM | 6.16 |
| CHEMBL4441173 | — | IC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL4434955 | — | IC50 | < | 180.0 | nM | - |