Assay Detail
Functional
CHEMBL4421792
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R46 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as activation of 3 uM strychnine-induced intracellular calcium level by FLIPR assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Antagonists and agonists of bitter taste receptors and uses thereof
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 5.37 | 5.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4446651 | — | — | 1 | 5.96 |
| CHEMBL4564347 | — | — | 1 | 5.08 |
| CHEMBL4435198 | — | — | 1 | 5.07 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4446651 | — | EC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL4564347 | — | EC50 | = | 8300.0 | nM | 5.08 |
| CHEMBL4435198 | — | EC50 | = | 8600.0 | nM | 5.07 |