Assay Detail
Functional
CHEMBL4421997
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by CT-Glo cytotoxicity assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Novel drug targets to overcome de novo drug-resistance in multiple myeloma
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.44 | 4.59 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1186087 | — | — | 1 | 4.59 |
| CHEMBL1413199 | DIPHENADIONE | 2.0 | 1 | 4.57 |
| CHEMBL4474391 | — | — | 1 | 4.43 |
| CHEMBL1534034 | — | — | 1 | 4.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1186087 | — | IC50 | = | 25900.0 | nM | 4.59 |
| CHEMBL1413199 | DIPHENADIONE | IC50 | = | 27200.0 | nM | 4.57 |
| CHEMBL4474391 | — | IC50 | = | 37100.0 | nM | 4.43 |
| CHEMBL1534034 | — | IC50 | = | 68500.0 | nM | 4.16 |