Assay Detail
Functional
CHEMBL4421998
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Cytotoxicity against human SK-UT-1 cells assessed as reduction in cell viability incubated for 72 hrs by CT-Glo cytotoxicity assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SK-UT-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Novel drug targets to overcome de novo drug-resistance in multiple myeloma
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.42 | 4.59 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1186087 | — | — | 1 | 4.59 |
| CHEMBL1413199 | DIPHENADIONE | 2.0 | 1 | 4.54 |
| CHEMBL4474391 | — | — | 1 | 4.30 |
| CHEMBL1534034 | — | — | 1 | 4.26 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1186087 | — | IC50 | = | 25500.0 | nM | 4.59 |
| CHEMBL1413199 | DIPHENADIONE | IC50 | = | 29200.0 | nM | 4.54 |
| CHEMBL4474391 | — | IC50 | = | 50400.0 | nM | 4.30 |
| CHEMBL1534034 | — | IC50 | = | 55300.0 | nM | 4.26 |