Assay Detail
Binding
CHEMBL4422702
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to recombinant human C-terminal His-tagged GLS1 after 3 hrs in presence of glycine by GDH coupled assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Glutaminase kidney isoform, mitochondrial (CHEMBL2146302) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Overview of the Development of Glutaminase Inhibitors: Achievements and Future Directions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 6.70 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2177757 | — | — | 1 | 6.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2177757 | — | Kd | = | 200.0 | nM | 6.70 |