Assay Detail

CHEMBL4422703

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Antiproliferative activity against human MDA-MB-231met2 cells

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Overview of the Development of Glutaminase Inhibitors: Achievements and Future Directions.

Xu X, Meng Y, Li L, Xu P, Wang J, Li Z, Bian J.
J Med Chem (2019) 62 : 1096 -1115
PubMed 30148361 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	8.70	8.70

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL3639788	TELAGLENASTAT	2.0	1	8.70

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL3639788	TELAGLENASTAT	IC50	=	2.0	nM	8.70