Assay Detail
Binding
CHEMBL4422717
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Inhibition of KGA (unknown origin) using glutamine as substrate preincubated for 20 mins followed by substrate addition and measured after 2 hrs
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Overview of the Development of Glutaminase Inhibitors: Achievements and Future Directions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.90 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4556013 | — | — | 1 | 7.00 |
| CHEMBL2177757 | — | — | 1 | 6.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4556013 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL2177757 | — | IC50 | = | 160.0 | nM | 6.80 |