Assay Detail

CHEMBL4423127

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Cytotoxicity against patient derived GSC after 96 hrs by CellTiter-Glo assay

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Unchecked (CHEMBL612545) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Recent advances in the discovery of small molecules targeting glioblastoma.

Fernandes GFDS, Fernandes BC, Valente V, Dos Santos JL.
Eur J Med Chem (2019) 164 : 8 -26
PubMed 30583248 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	7.51	7.51

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL964	DISULFIRAM	4.0	1	7.51

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL964	DISULFIRAM	IC50	=	31.1	nM	7.51