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Assay Detail

CHEMBL4423803

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Functional
Antiparasitic activity against Toxoplasma gondii VAND isolated from human and measured after 72 hrs by luciferase assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Toxoplasma gondii
Confidence 1 — Organism
Curated By Autocuration

Target

Toxoplasma gondii (CHEMBL612888)
Type ORGANISM
Organism Toxoplasma gondii

Publication

Discovery of Selective Toxoplasma gondii Dihydrofolate Reductase Inhibitors for the Treatment of Toxoplasmosis.
Hopper AT, Brockman A, Wise A, Gould J, Barks J, Radke JB, Sibley LD, Zou Y, Thomas S.
J Med Chem (2019) 62 : 1562 -1576
PubMed 30624926 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 7.95 7.95

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4468777 FANOTAPRIM 1.0 1 7.95

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4468777 FANOTAPRIM EC50 = 11.2 nM 7.95