Assay Detail
Binding
CHEMBL4424569
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of soybean lipoxygenase using sodium linoleate as substrate by UV-based analysis
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Glycine max |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
New Quinolylnitrones for Stroke Therapy: Antioxidant and Neuroprotective ( Z)- N- tert-Butyl-1-(2-chloro-6-methoxyquinolin-3-yl)methanimine Oxide as a New Lead-Compound for Ischemic Stroke Treatment.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.69 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL52 | NORDIHYDROGUAIARETIC ACID | — | 1 | 6.30 |
| CHEMBL4539028 | — | — | 1 | 4.49 |
| CHEMBL4575147 | — | — | 1 | 4.44 |
| CHEMBL1627056 | — | — | 1 | 4.24 |
| CHEMBL4456073 | — | — | 1 | 4.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL52 | NORDIHYDROGUAIARETIC ACID | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL4539028 | — | IC50 | = | 32500.0 | nM | 4.49 |
| CHEMBL4575147 | — | IC50 | = | 36500.0 | nM | 4.44 |
| CHEMBL1627056 | — | IC50 | = | 57500.0 | nM | 4.24 |
| CHEMBL4456073 | — | IC50 | = | 100000.0 | nM | 4.00 |