Assay Detail
Binding
CHEMBL4424701
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Inhibition of Staphylococcus aureus USA300 LAC quorum sensing system Agr assessed as reduction in AIP production measured after 5 hrs by UPLC-MS analysis
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Staphylococcus aureus subsp. aureus USA300 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Prenylated Diresorcinols Inhibit Bacterial Quorum Sensing.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.63 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4571412 | — | — | 1 | 6.52 |
| CHEMBL562502 | — | — | 1 | 5.89 |
| CHEMBL4535499 | — | — | 1 | 5.34 |
| CHEMBL290932 | — | — | 1 | 5.20 |
| CHEMBL4564181 | — | — | 1 | 5.20 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4571412 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL562502 | — | IC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL4535499 | — | IC50 | = | 4600.0 | nM | 5.34 |
| CHEMBL290932 | — | IC50 | = | 6300.0 | nM | 5.20 |
| CHEMBL4564181 | — | IC50 | = | 6300.0 | nM | 5.20 |