Assay Detail
Binding
CHEMBL4424969
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]-CP55940 from recombinant human CB1 receptor expressed in Sf9 cell membranes co-expressing Galphai3beta1gamma2 measured after 90 mins by scintillation counting method
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Sf9 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Plant-Based Modulators of Endocannabinoid Signaling.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 6.40 | 7.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL74415 | CANNABINOL | 3.0 | 1 | 7.89 |
| CHEMBL465718 | DELTA9-TETRAHYDROCANNABINOLIC ACID A | — | 1 | 7.62 |
| CHEMBL422704 | CANNABICHROMENE | — | 1 | 6.15 |
| CHEMBL497318 | CANNABIGEROL | 2.0 | 1 | 6.05 |
| CHEMBL190461 | CANNABIDIOL | 4.0 | 1 | 5.84 |
| CHEMBL2387742 | CANNABIDIVARIN | 2.0 | 1 | 4.83 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL74415 | CANNABINOL | Ki | = | 13.0 | nM | 7.89 |
| CHEMBL465718 | DELTA9-TETRAHYDROCANNABINOLIC ACID A | Ki | = | 24.0 | nM | 7.62 |
| CHEMBL422704 | CANNABICHROMENE | Ki | = | 714.0 | nM | 6.15 |
| CHEMBL497318 | CANNABIGEROL | Ki | = | 897.0 | nM | 6.05 |
| CHEMBL190461 | CANNABIDIOL | Ki | = | 1459.0 | nM | 5.84 |
| CHEMBL2387742 | CANNABIDIVARIN | Ki | = | 14710.0 | nM | 4.83 |