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Assay Detail

CHEMBL4424987

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [3H]-CP55940 from recombinant human CB1 receptor expressed in HEK293-EBNA cell membranes after 90 mins by scintillation counting method
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cannabinoid receptor 1 (CHEMBL218)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Plant-Based Modulators of Endocannabinoid Signaling.
Cunningham CW.
J Nat Prod (2019) 82 : 636 -646
PubMed 30816712 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 3 5.46 5.71

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL426912 1 5.71
CHEMBL463546 1 5.21
CHEMBL2287715 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL426912 Ki = 1940.0 nM 5.71
CHEMBL463546 Ki = 6210.0 nM 5.21
CHEMBL2287715 Ki > 40000.0 nM -