Assay Detail
Functional
CHEMBL4425215
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Antimalarial activity against Plasmodium falciparum 3D7 after 96 hrs
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antimalarial Chemotherapy: Natural Product Inspired Development of Preclinical and Clinical Candidates with Diverse Mechanisms of Action.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.82 | 7.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL529 | AZITHROMYCIN | 4.0 | 1 | 7.28 |
| CHEMBL1753 | CLINDAMYCIN | 4.0 | 1 | 6.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL529 | AZITHROMYCIN | IC50 | = | 53.0 | nM | 7.28 |
| CHEMBL1753 | CLINDAMYCIN | IC50 | = | 450.0 | nM | 6.35 |