Assay Detail
Binding
CHEMBL4425229
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of EML4-ALK variant 1 (unknown origin) expressed in BA/F3 cells assessed as decrease in cell viability after 24 hrs by CellTiter-Glo assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Development of Heat Shock Protein (Hsp90) Inhibitors To Combat Resistance to Tyrosine Kinase Inhibitors through Hsp90-Kinase Interactions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.96 | 7.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2103879 | GANETESPIB | 3.0 | 1 | 7.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2103879 | GANETESPIB | IC50 | = | 11.0 | nM | 7.96 |