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Assay Detail

CHEMBL4426076

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Binding
Inhibition of human plasmin using chromozyme PL as substrate by spectrophotometric method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Plasminogen (CHEMBL1801)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Optimization of Cyclic Plasmin Inhibitors: From Benzamidines to Benzylamines.
Hinkes S, Wuttke A, Saupe SM, Ivanova T, Wagner S, Knörlein A, Heine A, Klebe G, Steinmetzer T.
J Med Chem (2016) 59 : 6370 -6386
PubMed 27280436 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.66 8.66

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4471466 1 8.66

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4471466 Ki = 2.2 nM 8.66