Assay Detail
Binding
CHEMBL4426535
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Inhibition of wild type Staphylococcus aureus RNA polymerase assessed as reduction in RNA product formation
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Staphylococcus aureus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Development of a Dual-Acting Antibacterial Agent (TNP-2092) for the Treatment of Persistent Bacterial Infections.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.65 | 7.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL374478 | RIFAMPIN | 4.0 | 1 | 7.82 |
| CHEMBL1275685 | — | — | 1 | 7.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL374478 | RIFAMPIN | IC50 | = | 15.0 | nM | 7.82 |
| CHEMBL1275685 | — | IC50 | = | 34.0 | nM | 7.47 |