Assay Detail
Functional
CHEMBL4427073
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Antischistosomal activity against adult male Schistosoma mansoni BH assessed as inhibition of parasite motility up to 72 hrs by HCS microscopic analysis
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Schistosoma mansoni |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of New Anti-Schistosomal Hits by Integration of QSAR-Based Virtual Screening and High Content Screening.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 4.85 | 5.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1380406 | — | — | 1 | 5.19 |
| CHEMBL4534899 | — | — | 1 | 4.99 |
| CHEMBL4522839 | — | — | 1 | 4.68 |
| CHEMBL594404 | — | — | 1 | 4.53 |
| CHEMBL4556222 | — | — | 1 | - |
| CHEMBL1455317 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1380406 | — | EC50 | = | 6430.0 | nM | 5.19 |
| CHEMBL4534899 | — | EC50 | = | 10200.0 | nM | 4.99 |
| CHEMBL4522839 | — | EC50 | = | 21100.0 | nM | 4.68 |
| CHEMBL594404 | — | EC50 | = | 29800.0 | nM | 4.53 |
| CHEMBL4556222 | — | EC50 | - | — | - | |
| CHEMBL1455317 | — | EC50 | - | — | - |