Assay Detail
Functional
CHEMBL4428222
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Antiproliferative activity against human LTEP-G2 cells after 72 hrs by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Discovery of New Monocarbonyl Ligustrazine-Curcumin Hybrids for Intervention of Drug-Sensitive and Drug-Resistant Lung Cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.41 | 5.63 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4475597 | — | — | 1 | 5.63 |
| CHEMBL4451948 | — | — | 1 | 5.54 |
| CHEMBL4458105 | — | — | 1 | 5.36 |
| CHEMBL4521088 | — | — | 1 | 5.30 |
| CHEMBL4442682 | — | — | 1 | 5.23 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4475597 | — | IC50 | = | 2340.0 | nM | 5.63 |
| CHEMBL4451948 | — | IC50 | = | 2880.0 | nM | 5.54 |
| CHEMBL4458105 | — | IC50 | = | 4360.0 | nM | 5.36 |
| CHEMBL4521088 | — | IC50 | = | 5010.0 | nM | 5.30 |
| CHEMBL4442682 | — | IC50 | = | 5910.0 | nM | 5.23 |