Assay Detail
ADMET
CHEMBL4428223
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Cytotoxicity against NHBE cells after 72 hrs by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Discovery of New Monocarbonyl Ligustrazine-Curcumin Hybrids for Intervention of Drug-Sensitive and Drug-Resistant Lung Cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.75 | 4.84 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4475597 | — | — | 1 | 4.84 |
| CHEMBL4458105 | — | — | 1 | 4.79 |
| CHEMBL4521088 | — | — | 1 | 4.75 |
| CHEMBL4442682 | — | — | 1 | 4.68 |
| CHEMBL4451948 | — | — | 1 | 4.67 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4475597 | — | IC50 | = | 14350.0 | nM | 4.84 |
| CHEMBL4458105 | — | IC50 | = | 16230.0 | nM | 4.79 |
| CHEMBL4521088 | — | IC50 | = | 17560.0 | nM | 4.75 |
| CHEMBL4442682 | — | IC50 | = | 20760.0 | nM | 4.68 |
| CHEMBL4451948 | — | IC50 | = | 21340.0 | nM | 4.67 |