Assay Detail
ADMET
CHEMBL4428536
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Cytotoxicity against TAMH assessed as reduction in cell viability by CellTiter-Glo assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Mus musculus |
| Cell Type | TAMH |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Overcoming chloroquine resistance in malaria: Design, synthesis and structure-activity relationships of novel chemoreversal agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.76 | 4.76 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL24999 | — | — | 1 | 4.76 |
| CHEMBL4472492 | — | — | 1 | - |
| CHEMBL4449669 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL24999 | — | IC50 | = | 17200.0 | nM | 4.76 |
| CHEMBL4472492 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL4449669 | — | IC50 | = | 101100.0 | nM | - |