Assay Detail
ADMET
CHEMBL4428537
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human AC10 cells assessed as reduction in cell viability by CellTiter-Glo assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Overcoming chloroquine resistance in malaria: Design, synthesis and structure-activity relationships of novel chemoreversal agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.25 | 4.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4449669 | — | — | 1 | 4.34 |
| CHEMBL4472492 | — | — | 1 | 4.15 |
| CHEMBL24999 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4449669 | — | IC50 | = | 45190.0 | nM | 4.34 |
| CHEMBL4472492 | — | IC50 | = | 71470.0 | nM | 4.15 |
| CHEMBL24999 | — | IC50 | - | — | - |