Assay Detail
Binding
CHEMBL4429015
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Competitive binding affinity to recombinant mouse galectin-7 after 5 mins in presence of fluorescent probe beta-D-galactopyranosyl(1-4)-2- acetamido-2-deoxy-beta-D-glucopyranosyl(1-3)-beta-D-galactopyranosyl(1-4)-(N1-fluorescein-5-yl-carbonylaminomethylcarbonyl)-beta-D-glucopyranosylamine by fluorescence polarization assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
A Selective Galactose-Coumarin-Derived Galectin-3 Inhibitor Demonstrates Involvement of Galectin-3-glycan Interactions in a Pulmonary Fibrosis Model.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 4.94 | 5.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL444662 | — | — | 1 | 5.77 |
| CHEMBL4446622 | — | — | 1 | 5.30 |
| CHEMBL4519227 | — | — | 1 | 4.47 |
| CHEMBL4588244 | — | — | 1 | 4.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL444662 | — | Kd | = | 1700.0 | nM | 5.77 |
| CHEMBL4446622 | — | Kd | = | 5000.0 | nM | 5.30 |
| CHEMBL4519227 | — | Kd | = | 34000.0 | nM | 4.47 |
| CHEMBL4588244 | — | Kd | = | 60000.0 | nM | 4.22 |