Assay Detail
Binding
CHEMBL4430058
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of PI3Kdelta in rat B cells assessed as reduction in anti-rat IgM/rIL-4 stimulated CD86 expression preincubated for 1 hr followed by anti-rat IgM/rIL-4 stimulation for 24 hrs by flow cytometry
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Discovery and Pharmacological Characterization of Novel Quinazoline-Based PI3K Delta-Selective Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.36 | 7.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3977066 | — | — | 1 | 7.36 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3977066 | — | IC50 | = | 44.0 | nM | 7.36 |