Assay Detail
Binding
CHEMBL4430787
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of porcine kidney microsomal LAP using l-leucine-7-amido-4-methylcoumarin as substrate incubated for 10 hrs measured every 6 mins by fluorescence assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Tissue | Kidney |
| Subcellular | Microsomal |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Molecular docking studies, biological and toxicity evaluation of dihydroisoquinoline derivatives as potential anticancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.71 | 4.95 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL29292 | UBENIMEX | 2.0 | 1 | 4.95 |
| CHEMBL4483393 | — | — | 1 | 4.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL29292 | UBENIMEX | IC50 | = | 11200.0 | nM | 4.95 |
| CHEMBL4483393 | — | IC50 | = | 33600.0 | nM | 4.47 |