Assay Detail
ADMET
CHEMBL4430793
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Antiproliferative activity against mouse BALB/3T3 cells after 72 hrs by SRB assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Mus musculus |
| Cell Type | BALB/3T3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Molecular docking studies, biological and toxicity evaluation of dihydroisoquinoline derivatives as potential anticancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 4.31 | 4.45 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4483393 | — | — | 1 | 4.45 |
| CHEMBL4467841 | — | — | 1 | 4.16 |
| CHEMBL4537106 | — | — | 1 | - |
| CHEMBL4455383 | — | — | 1 | - |
| CHEMBL4557950 | — | — | 1 | - |
| CHEMBL4576374 | — | — | 1 | - |
| CHEMBL4454667 | — | — | 1 | - |
| CHEMBL4456116 | — | — | 1 | - |
| CHEMBL4435767 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4483393 | — | IC50 | = | 35900.0 | nM | 4.45 |
| CHEMBL4467841 | — | IC50 | = | 68600.0 | nM | 4.16 |
| CHEMBL4537106 | — | IC50 | = | 235200.0 | nM | - |
| CHEMBL4455383 | — | IC50 | = | 1831300.0 | nM | - |
| CHEMBL4557950 | — | IC50 | = | 2078600.0 | nM | - |
| CHEMBL4576374 | — | IC50 | = | 1264000.0 | nM | - |
| CHEMBL4454667 | — | IC50 | = | 182800.0 | nM | - |
| CHEMBL4456116 | — | IC50 | = | 1963100.0 | nM | - |
| CHEMBL4435767 | — | IC50 | = | 929000.0 | nM | - |